Clarithromycin associated with torsades de pointes.

نویسندگان

  • H Kamochi
  • T Nii
  • K Eguchi
  • T Mori
  • A Yamamoto
  • K Shimoda
  • K Ibaraki
چکیده

Two cases of QT prolongation and torsades de pointes (TdP) are presented. The patients had been taking clarithromycin (400 mg/day) for respiratory disease. Although erythromycin is reportedly associated with TdP, this is the first report of clarithromycin associated with TdP in the absence of other drugs already known to produce QT prolongation.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Torsades de Pointes (TdP) after Taking Prenylamine

L'intervalle de temps variable existante entre le debut du traitement par la prenylamine et la sur­venu de toisade de pointe et d'autre oart la raretee de· telle camplication est considere par les auteurs c0mme une indice de !'intervention de d'autres fac­teurs, parmie Jes quelles, la perturbation electroly­tique doit jouer le role principal. 

متن کامل

Torsades de pointes: Should ECG be taken from all patients before surgery? A case report

Torsades de pointes is a rare but potentially lethal arrhythmia which mainly occurs in the setting of a prolonged QT interval. ECG is a reliable tool to detect such abnormalities, routinely taken from all patients over 40 who undergo surgery. We describe the case of a 35-year-old woman with torsades de points arrhythmia after hysterectomy surgery. Most likely, our patients had long QT syndro...

متن کامل

Rationing in the NHS: audit of outcome and acceptance of restriction criteria for minor operations.

zolam on 261 occasions (this combination may increase the central depressant effects of alprazolam) and with carbamazepine on 240 (this combination may cause serious toxic effects by increasing plasma concentrations of carbamazepine). Cisapride was dispensed with erythromycin on five occasions, with clarithromycin on three, fluconazole on 24, and itraconazole on one; any of these combinations m...

متن کامل

Clarithromycin-Induced Long QT Syndrome: A Case Report

Long QT syndrome develops for a number of reasons. The number of non-antiarrhythmic drugs reported to induce QT interval prolongation with or without torsade de pointes continues to increase. Clarithromycin is a macrolide antibiotic being increasingly used for the treatment of atypical pneumonia. In this paper, we describe a patient who developed long QT prolongation syndrome after receiving cl...

متن کامل

[Ventricular tachycardia and long QT associated with clarithromycin administration in a patient with HIV infection].

Prolongation of the QT interval is associated with a high risk of serious ventricular tachyarrhythmias, usually torsade de pointes (TdP) polymorphic ventricular tachycardia, although monomorphic ventricular tachycardia may also develop. Both congenital and acquired forms have been reported, acquired forms being much more prevalent. An association between human immunodeficiency virus (HIV) infec...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Japanese circulation journal

دوره 63 5  شماره 

صفحات  -

تاریخ انتشار 1999